Association between Lung Microbiota Dysbiosis and Sepsis Induced Acute Respiratory Distress Syndrome
نویسندگان
چکیده
Sepsis is associated with acute respiratory distress syndrome, which has a significant impact on the prognosis of patients. Several studies have shown that microbiota plays role in sepsisinduced but relationship between and syndrome not fully understood. We conducted case-control single-center study 19 sepsis-induced patients 36 sepsis-noninduced to investigate clinical features expression. There were 55 subjects enrolled, whom suffered due sepsis. A increase abundance Pseudomonas aeruginosa, leptospiral virus, Cytomegalovirus, Klebsiella pneumoniae, Streptococcus Candida albicans, Escherichia coli, Epstein-Barr virus Staphylococcus aureus. Besides, expressions peripheral T lymphocytes (cluster differentiation 3+, cluster 4+ 8+) was much higher group than sepsis non-induced group. The physiology chronic health evaluation II scores, duration mechanical ventilation mortality 28 d 90 Patients had worse outcomes expression lymphocytes, as well relative dysbiosis.
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2023
ISSN: ['0250-474X', '1998-3743']
DOI: https://doi.org/10.36468/pharmaceutical-sciences.spl.692